Myocardial blood flow in coronary artery disease. Effect of right atrial pacing and nitroglycerin.
نویسندگان
چکیده
Sixteen patients, 10 with significant three-vessel coronary artery disease (>50% occlusion of each vessel) and six without coronary disease, had nutrient myocardial blood flow, cardiac output, pressure time/ min and arterial pressure determinations at rest, with atrial pacing and with right atrial pacing plus nitroglycerin. In the patients with coronary disease, nutrient myocardial blood decreased an average of 16% (P < 0.001) with pacing alone but increased by 22% (P < 0.001) from the pacing flows with the addition of 0.4 mg sublingual nitroglycerin at the same pacing rate. The directional changes in myocardial blood flow were unrelated to perfusion pressure or pressure work. In the patients without coronary dis-
منابع مشابه
Myocardial Blood Flow in Coronary Artery Disease Effect of Right Atrial Pacing and Nitroglycerin SUZANNE
Sixteen patients, 10 with significant three-vessel coronary artery disease (>50% occlusion of each vessel) and six without coronary disease, had nutrient myocardial blood flow, cardiac output, pressure time/ min and arterial pressure determinations at rest, with atrial pacing and with right atrial pacing plus nitroglycerin. In the patients with coronary disease, nutrient myocardial blood decrea...
متن کاملMyocardial Blood Flow in Coronary Artery Disease
Sixteen patients, 10 with significant three-vessel coronary artery disease (>50% occlusion of each vessel) and six without coronary disease, had nutrient myocardial blood flow, cardiac output, pressure time/ min and arterial pressure determinations at rest, with atrial pacing and with right atrial pacing plus nitroglycerin. In the patients with coronary disease, nutrient myocardial blood decrea...
متن کاملEffects of nitroglycerin on regional myocardial ischemia induced by atrial pacing in dogs.
The exact mechanism or mechanisms by which nitroglycerin exerts its beneficial effect on pacing-induced regional myocardial ischemia has not been ellucidated previously. In an open-chest, anesthetized canine preparation a fixed, flow limiting stenosis was applied to the left anterior descending (LAD) coronary artery and heart rate was increased by atrial pacing. Mass spectrometry was used to me...
متن کاملShort-term effects of right atrial, right ventricular apical, and atrioventricular sequential pacing on myocardial oxygen consumption and cardiac efficiency in patients with coronary artery disease.
OBJECTIVE To investigate the short-term effects of atrial, atrioventricular, and ventricular pacing on myocardial oxygen consumption, myocardial blood flow, and cardiac efficiency in patients with coronary artery disease. DESIGN Prospective study that started at the end of diagnostic coronary angiography in 13 patients and was performed during atrial, atrioventricular, and ventricular pacing ...
متن کاملCoronary sinus reflux. A source of error in the measurement of thermodilution coronary sinus flow.
In seven patients thermodilution coronary sinus flow (TD-CSF) was higher (164 +/- 21 ml/min) during ventricular pacing than during atrial pacing (119 +/- 21 ml/min, P less than 0.005) at identical heart rate, without an increase in the determinants of myocardial oxygen consumption. To assess the possibility of right atrial admixture in coronary sinus blood during ventricular pacing we compared ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Circulation
دوره 47 4 شماره
صفحات -
تاریخ انتشار 1973